What is Neurofibromatosis (NF)?
Neurofibromatosis Type 1 is the most common genetic disorder linked to a single gene, affecting 1 in 3,000.
Forms: NF1, NF2, Schwannomatosis
Neurofibromatosis (NF) is an inclusive term used to describe three autosomal dominant genetic conditions (NF1, NF2, and Schwannomatosis) characterized by tumor growth on and around nerve tissue. Symptoms include tumor growth; cardiovascular, skeletal, and endocrine issues; chronic pain; hearing and vision loss; and cognitive challenges, among others. Recent research has reported anxiety and depression rates about 40% and high rates of attention and cognitive difficulties in NF-affected populations. NF is estimated to affect 1 in every 3,000 births.
To date there are no effective treatments
- Tumors anywhere in the body (particularly brain & spine)
- Behavioral, attention, and social challenges
- Cardiovascular complications
- Significant learning disorders
- Hard-to-treat cancers
- Serious musculoskeletal abnormalities
- Blindness & deafness